Jacob Hessel Klein was a son of Calmer Klein and Rachel van Gelder.
He married Roosje Vos in 1914 in Coevorden. She died in 1926. Jacob Hessel later married Frederika Cozijn.
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Jacob Hessel Klein was head of the food supply department of the Apeldoornse Bos, where he began working on 16 March 1925. He was a widower of Roosje Vos, and a merchant by trade.
Jacob Hessel Klein attended the marriage of his son Karel Martin Klein to Eleonora Poppers. The marriage ceremony was performed in Westerbork transit camp on 18 February 1943. He signed the marriage certificate. Archives of the Apeldoorn municipality, staff list of Het Apeldoornse Bos;
Record of marriage certificates of the Westerbork municipality, currently at the archives of Gemeente Midden-Drenthe in Beilen
According to the archive of the Apeldoornse Bos it was tried to get Jacob Hessel Klein with his family out of Westerbork, with the reason that he was indispensable for the Apeldoornse Bos.
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