Meijer de Lieme was a son of Nathan de Lieme and Jantje or Jansje Manheim. He married Anna Rachel Italie in Lemmer on 1 September 1897, a daughter of Asser Italie and Sophia Eckstein. The couple had four children, of whom two have died in infancy, only a few months old. The other two children of Meijer and Anna Rachel were Jansje and Herman Isidor. Both have been killed in the Shoah.
Meijer de Lie…